Reduce complications1,2

  • Treat exacerbations: Appropriate management of lung-related acute exacerbations includes antibiotics to help treat exacerbations of COPD and other bacterial infections
  • Supplemental oxygen: Increases exercise capacity in alpha-1-antitrypsin (A1AT) deficiency (also known as alpha-1) patients with desaturation. Recommended at advanced stages of lung disease and when indicated by conventional criteria (eg, during air travel)

Noninvasive ventilator support may also be recommended for patients with stable, severe lung disease.

References

  1. American Thoracic Society/European Respiratory Society statement: standards for the diagnosis and management of individuals with alpha-1 antitrypsin deficiency. Am J Respir Crit Care Med. 2003;168:818-900.
  2. Global Initiative for Chronic Obstructive Lung Disease. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease. 2016. http://goldcopd.org/global-strategy-diagnosis-management-prevention-copd-2016/. Accessed July 14, 2016.

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