Reduce complications1,2

  • Treat exacerbations: Appropriate management of lung-related acute exacerbations includes antibiotics to help treat exacerbations of COPD and other bacterial infections
  • Supplemental oxygen: Increases exercise capacity in alpha-1-antitrypsin (A1AT) deficiency (also known as alpha-1) patients with desaturation. Recommended at advanced stages of lung disease and when indicated by conventional criteria (eg, during air travel)


  1. American Thoracic Society/European Respiratory Society statement: standards for the diagnosis and management of individuals with alpha-1 antitrypsin deficiency. Am J Respir Crit Care Med. 2003;168:818-900.
  2. Global Initiative for Chronic Obstructive Lung Disease. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease. 2016. Accessed July 14, 2016.

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